P17.06: Screening for trisomies and fetal anomalies in the second trimester after first trimester genetic scan. What are the benefits?
نویسندگان
چکیده
منابع مشابه
Sonographic markers of fetal trisomies: second trimester.
OBJECTIVE Second-trimester sonographic findings of fetal trisomy may include structural abnormalities or sonographic markers of fetal aneuploidy. Unlike structural anomalies, sonographic markers of fetal aneuploidy are insignificant by themselves with regard to outcome, are nonspecific--most frequently seen in normal fetuses, and are often transient. Our objective was to review the second-trime...
متن کاملFirst trimester ultrasonography in screening and detection of fetal anomalies.
An obstetrical ultrasound examination provides invaluable information regarding the fetus. Until the mid-1980s, ultrasound in the first trimester was limited to localization of the pregnancy, establishing viability, and accurate dating. With the advent of high-resolution ultrasound and transvaginal scanning, a significant amount of information about the fetus can be gained and provided to the p...
متن کاملSecond-trimester genetic sonography after first-trimester combined screening for trisomy 21.
OBJECTIVE The purpose of this study was to evaluate the trisomy 21 screening performance of the first-trimester combined test followed by second-trimester genetic sonography. METHODS This retrospective cohort study included all women with singleton pregnancies undergoing combined screening followed by genetic sonography at 17 to 21 weeks from January 1, 2005, to January 31, 2008. Combined tes...
متن کاملFirst-trimester screening for trisomies 21 and 18.
BACKGROUND Screening for aneuploid pregnancies is routinely performed after 15 weeks of gestation and has a sensitivity of approximately 65 percent, with a false positive rate of 5 percent. First-trimester markers of aneuploidy have been developed, but their use in combination has not been adequately evaluated in clinical practice. METHODS We conducted a multicenter study of screening for tri...
متن کاملNoninvasive prenatal testing (NIPT) for fetal trisomies in a routinely first-trimester screening
Results Results from chromosome selective sequencing were available from 253 cases of 255 cases. In two cases fetal cell fraction was below the minimal requirement of 4%. In this population of 255 cases we found euploid pregnancies in 250 cases and 5 aneuploid pregnancies: two trisomies 21, one trisomy 18, one triosmy 13 and one 45 XO. In 195 pregnant women, the performance of screening by comb...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics and Gynecology
سال: 2010
ISSN: 0960-7692
DOI: 10.1002/uog.8544